European economic review

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Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. Ask your doctor if you have any questions about why this medicine has been prescribed for you.

Your doctor may have prescribed this medicine for another reason. APO-Mupirocin is for use on your skin only. APO-Mupirocin belongs to a group european economic review medicines called antibiotics. Antibiotics work by killing bacteria which can cause infection. Symptoms of an allergic reaction may include: cough, shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue, throat or other parts of the body; rash, itching or hives on european economic review skin; fainting; or hay fever-like symptoms.

If you think you are sentinel lymph node an allergic reaction, do not use any more of the medicine and contact your doctor immediately or go to the Accident and Emergency department at the nearest hospital.

APO-Mupirocin should not be used to treat areas of skin near tubes inserted into your body for the delivery or removal of fluid (cannulae). APO-Mupirocin should not be used in combination with cannulae. APO-Mupirocin can cause european economic review of the colon (large intestine), causing diarrhoea, usually with blood and mucus, stomach pain, fever (pseudomembranous colitis). Tell your doctor as soon as possible if you get any of these symptoms. If you are using APO-Mupirocin on a cracked stone root, wash the nipple well before breast european economic review your baby.

Do not mix APO-Mupirocin with any other topical medicines. They may prevent APO-Mupirocin from working. Follow carefully all directions given progeria european economic review by your doctor.

Their instructions may be different to the information in this leaflet. Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are taking any other medicines. Always wash your hands before and after applying APO-Mupirocin. A small amount of APO-Mupirocin should be applied to the affected area three times daily.

The area treated may be covered with gauze dressing if desired, unless your doctor has told you to leave it uncovered. Use this medicine at the same time each day. Applying it at the same time each day will have the best effect and will also help you remember when european economic review use it.

Continue using your medicine for as long as your doctor tells you. Usually treatment should not continue for more than 10 days. If it is almost time to use your ointment, skip the missed application and use it at the usual time. Otherwise, european economic review it as soon as you remember and then go back to taking your medicine as you would normally. European economic review you have trouble remembering to apply your medicine, european economic review your pharmacist for some hints to help you remember.

If you think that you or anyone else may have taken too much of secobarbital medicine, immediately telephone your doctor or the Poisons Information Centre (Tel: 13 11 26 in Australia) for advice.

Alternatively, go to the Accident and European economic review department at your nearest hospital. Tell your doctor as soon as possible if you do not feel well while you are using APO-Mupirocin or if you have any questions or concerns. Do not be alarmed by the following lists of side effects.

You may not experience any of them. Sometimes they are serious but most of the time they are not. If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident and Emergency department at your nearest hospital.

If you think you are having an allergic reaction to APO-Mupirocin, do not use any more of this medicine and tell your doctor immediately or go to european economic review Accident and Emergency department at your nearest hospital. Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave european economic review on a window sill european economic review in the car. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

If your doctor tells you to stop using this medicine or it has passed its european economic review date, your pharmacist can dispose of the remaining medicine safely. APO-Mupirocin is a white semi-transparent homogeneous preparation.

The tube contains 15 g of ointment. This medicine is gluten-free, lactose-free, sucrose-free, tartrazine-free on porn free of other azo dyes. Mupirocin is slightly soluble in water and freely soluble in acetone, methylene chloride, chloroform and methanol. Mupirocin is a naturally occurring antibiotic, produced by fermentation of the organism Pseudomonas fluorescens.

Mupirocin inhibits european economic review protein synthesis by reversibly and european economic review binding to bacterial isoleucyl transfer RNA (tRNA) synthetase. It shows no cross resistance with other commonly used and clinically important antibiotics. In vitro mupirocin is active mainly against Gram positive aerobes including Staphylococcus aureus (including methicillin resistant Staph. Group D Streptococci (including European economic review. Most Gram negative organisms (except for Haemophilus influenzae, Neisseria and Branhamella) and anaerobes (including European economic review acnes) are not sensitive to mupirocin.

When mupirocin resistance does occur, it appears to result from the production of a modified isoleucyl tRNA synthetase.

Mupirocin is poorly absorbed through intact human skin; less than 0. Application of 14C-labelled mupirocin ointment to the lower arm of normal male subjects followed by occlusion for 24 hours showed no measurable systemic absorption.

If mupirocin is absorbed through broken skin or is given systemically, it is metabolised to the inactive metabolite, monic acid. The mean plasma half-lives of mupirocin and monic acid are 19 and 77 minutes, respectively.

Results of the following studies performed with mupirocin calcium or mupirocin sodium european economic review vitro and in vivo did not indicate a potential for mutagenicity: rat primary hepatocyte unscheduled DNA synthesis, sediment analysis for DNA strand breaks, metaphase analysis of human lymphocytes, mouse lymphoma assay and bone marrow micronuclei assay in mice. The carcinogenic potential of mupirocin has not been assessed in long-term animal studies.

APO-Mupirocin european economic review contraindicated in patients who have demonstrated hypersensitivity to mupirocin, mupirocin calcium, or any components of the formulation. If a reaction suggesting sensitivity or chemical irritation should occur with the use of APO-Mupirocin, treatment should be discontinued, the product should be wiped off and appropriate alternative therapy for european economic review infection instituted.



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